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Tirzepatide achieves #greater weight loss and glycemic control relative to semaglutide.3,4 However, #semaglutide is the most #validated GLP-1 medicine in outcome trials, with benefits demonstrated in #osteoarthritis, peripheral artery disease
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In this large-scale real-world study, individual GLP-1RAs and SGLT2Is exhibited largely comparable cardiovascular benefits, including in patients with established cardiovascular disease (CVD). These findings align with network meta-analytic estimates
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