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GLP-1 receptor agonists got their start in an unlikely place: the mouth of a lizard. A peptide that was discovered in Gila monster saliva, called exendin-4, was found to mimic the action
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Glucagon-Like Peptide-1 and Its Receptor Agonist Exendin-4 Modulate Cholangiocyte Adaptive Response to Cholestasis
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Comparison of Exendin-4 and Its Single Amino Acid Substitutions as Parent Peptides for GLP-1 Receptor Imaging Probes
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Strategies to Enhance the Therapeutic Efficacy of GLP‐1 Receptor Agonists through Structural Modification and Carrier Delivery - Zhang - 2025 - ChemBioChem
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Frontiers
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Acylation of the incretin peptide exendin-4 directly impacts GLP-1 receptor signalling and trafficking
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Exendin-4, a glucagon-like peptide 1 receptor agonist, protects cholangiocytes from apoptosis
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