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leptin vs glp 1 Hypothalamic anorexigenic signaling pathways (leptin, amylin, and proopiomelanocortin) are semaglutide (GLP-1 analog) targets in obesity control in mice

Marsoni M251S
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4.3 ★★★★★
Based on 412 reviews
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Nightbow
Louisville, US
★★★★★ 3
no substitute for Aveeno
Pros: There's no smell (yay--I don't get why folks say it smells like oatmeal; it doesn't, it just smells like it doesn't have perfume added), and it spreads well. BUT: it's too thin and doesn't last well enough. Had my first eczema flair in years while using this. I'm going back to Aveeno fragrance-free. At least I tried.
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Reviewed in the United States on December 22, 2023
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Verified Purchase
Amazon Customer
Chelsea, US
★★★★★ 4
its ok
its ok, has a lot of chemicals in it, but not 2% of colloidal oatmeal which is recommended for an eczema lotion. i like this brand because its cruelty free but this is not great for eczema. i actually like that it is not thick, but it doesnt calm my dry itchy skin very much.
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Reviewed in the United States on May 27, 2026
T
Verified Purchase
The Real Nowhere Man?
Dallas, US
★★★★★ 5
It’s a great all-round lotion, it does what it says it does.
It is one of the lightest moisturizers I’ve used, perfect for whole body. Though, naturally, using more makes it more moisturizing, and it does have a big pump. It spreads and absorbs well. It is not sticky, but silky. It calms itchy, irritated skin. It’s pH-balanced. It has very nice ingredients. It has a lot of nutrients skin needs. It is fragrance-free, though the aromatic alcohol preservatives impart a slight rose-almond odor. It’s a good price. It’s a nice bottle and pump. However, it would be nice if it were more reliably and widely available.
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Reviewed in the United States on November 3, 2024
E
Verified Purchase
eric watson
Fort Morgan, US
★★★★★ 5
Amazing lotion
Amazing lotion. Not too heavy. Feels great on the skin.
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Reviewed in the United States on May 13, 2025
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Verified Purchase
Suzanna
Grantham, US
★★★★★ 1
Sticky and unpleasant smelling
It’s thin and watery and leaves a sticky feeling on your skin that makes you want to wash your hands. It’s fragrance free but somehow has an unpleasant smell. The regular 365 brand fragrance free “moisturizing Lotion” that I normally buy when it’s available is MUCH better
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Reviewed in the United States on March 13, 2021

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