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First head-to-head trial compares tirzepatide and semaglutide - Results are in!
25.66
SURMOUNT‐1 study design. This is a phase 3, multicenter, randomized,
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Tirzepatide shows 47% greater weight loss vs. Wegovy
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In the SURMOUNT-4 trial, 82.5% of adults with obesity regained ≥25% of initial weight lost within one year of tirzepatide withdrawal; most showed reversal of cardiometabolic improvements. https://ja.ma/4qaMLfO
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Tirzepatide for the Maintenance of Body Weight Reduction: Rationale, Design, and Baseline Characteristics of SURMOUNT‐MAINTAIN - Horn - 2025 - Obesity
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Body composition changes during weight reduction with tirzepatide in the SURMOUNT‐1 study of adults with obesity or overweight - Look - 2025 - Diabetes, Obesity and Metabolism
25.80
