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glp-1 and ghrelin Gut hormones like ghrelin (↑ hunger) & GLP-1/PYY (↓ hunger) signal to the hypothalamus' arcuate nucleus. Orexigenic (AgRP/NPY) & anorexigenic (POMC/CART) neurons integrate these signals, regulating food intake via Y1/Y5 & Mc4

Marsoni M251S
Sale price$27.70
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Get it in 3 business days with 1 day shipping. Friday, May 29
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4.3 ★★★★★
Based on 157 reviews
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AmazonSmile
Massapequa, US
★★★★★ 5
Perfect fit every time
Color: Silver, Size: 30W x 30L
These original 874’s are the real deal. Stocked up during the sale and got them for my husband. He loves all the colors and the durability of these pants is incredible. He still has some from 14 years ago! But he wanted a few new ones- and they had more colors so I stocked up and surprised him when I told him how much they cost during the sale. These pants never wrinkle. I wash them hot and air dry- no wrinkling or shrinking. They look great. They’re sewn to perfection. The quality is there and has been for years, a reason my husband only wears these. Quality, value, durability, style, fit. Great for all seasons, they’re not too heavy or too light. Great functionality- pockets for everything . Great even in summer - they are very breathable. Perfect fit every time. Great for heavy road construction or just going for a hike. Highly recommend!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on November 22, 2025
M
Verified Purchase
Moises
Alexandria, US
★★★★★ 5
Good work pants
Color: Dark Brown, Size: 46W x 32L
run small / snug I would recommend getting next size up minimum.
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Reviewed in the United States on May 18, 2026
D
Verified Purchase
Diego
Draper, US
★★★★★ 5
Durable and great fit
Color: Black, Size: 32W x 34L
Great fit and quality, nice color, this are a work pants, pretty durable and they haven’t fade, also they don’t shrink or wrinkle
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Reviewed in the United States on April 15, 2026
L
Verified Purchase
LucasCoto
Alexandria, US
★★★★★ 4
Run small, size it up
Color: Mushroom, Size: 32W x 30L, Color: Mushroom, Size: 32W x 30L
They go small, Im 5'8", 165lbs, usually 32x30 fits just rigth in most brands Levis, Izod, whatever, can't even close the zipper on this one, my dingus prints in the front if I manage to close it, I will try a 34 or even 36, if you want one, size it up. Length is right. Anyway, the pant is good, sturdy looking material, is not soft but nothing uncomfortable probably gets right after break it in, reinforced stitches on pockets. I think they would work great for a technician, salesman or an engineer, those jobs where you have to look like a human being with a polo shirt but sometimes needs to do something without ripping your pants while crouching or for daily abuse of the regular Joe, will try another that fits
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Reviewed in the United States on May 28, 2026
R
Verified Purchase
Red
Lake Worth, US
★★★★★ 5
Best Value For The Money
Color: Black, Size: 36W x 32L
My grandson uses these for work. Well-made and durable. Worth the price. Fit is comfortable.
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Reviewed in the United States on April 13, 2026

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