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GLP 1 & GIP Mechanism (Incretin effect) GLP 1 and GIP are incretin hormones released from the intestine after meals. They improve metabolic control by: Enhancing glucose dependent insulin secretion Suppressing glucagon release Medicare will now cover weight loss drug semaglutide if taken for heart benefits Bioma Glp 1 Activator GLP ONE + Receptor Activator Doctors and patients across social media are reporting a kind of emotional flattening while on GLP 1 drugs. Anecdotally, physicians describe meaningful mental health gains greater self esteem, less shame over eating and Research in Nature Medicine tracked 14,979 adults and found that even ONE course of antibiotics can disrupt your gut microbiome for up to 8 years with lasting effects on metabolism, blood