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soul trial oral semaglutide cardiovascular outcomes soul trial results Congreso ACC. 25: Oral Semaglutide Reduces Cardiovascular Events in People With Type 2 Diabetes With Atherosclerotic Cardiovascular and/or Chronic Kidney Disease: Primary Results From the SOUL Randomized Trial

Marsoni M251S
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4.5 ★★★★★
Based on 1443 reviews
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Verified Purchase
Millie
Lexington, US
★★★★★ 5
Rough and tough chew toy
Color: Azure, Size: Large(50-90 lbs)
This is a thick and heavy duty toy to stand up to medium to large dogs who are heavy chewers. And the rough textures really encourages my dog and it is the perfect size to throw and play fetch. Very sturdy…I bought around Christmas and it’s almost may and she hasn’t destroyed it yet!!!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 26, 2026
C
Verified Purchase
Cindy Tuttle
Bozeman, US
★★★★★ 4
Very sturdy and strong toy
Color: Green, Size: Large(50-90 lbs)
This keeps my dog busy. He has a blast with it. It is a little bit big for his mouth, but he still seems to have fun with it. My dog is German Shepherd and Australian Shepherd.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 23, 2026
A
Verified Purchase
Andrew Georgen
San Leandro, US
★★★★★ 5
Awesome squeaker toy!
Color: Green, Size: Large(50-90 lbs)
Noise level is expected. It’s a squeak toy. If you get annoyed by your dog having fun, get outta here. It’s a bigger toy so I don’t worry about choking. It’s bouncy and a tough material for our tough chewer. Color is whatever! Great toy.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 30, 2026
D
Verified Purchase
Dione Ray
Louisville, US
★★★★★ 3
It was fun while it lasted.
Color: Green, Size: Large(50-90 lbs)
This is a tough chew toy, but yep, it still got destroyed after a few uses. So my Siberian Husky strategically destroys the squeak in everything immediately. This one actually took some time. It's not super squeaky and is more challenging to make it squeak. I was pleasantly surprised that it the squeaker lasted a couple weeks. For the record my Pitbull got to it the 3rd week and it was completely destroyed in 2 further days. This is a very hard chew toy and I wouldn't recommend this unless your dog is also a destroyer of a the tougher toys. Even though it was still demolished they had a great time with it and it still lasted longer than most. I hope that helps and I hope you have a happy day.
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Reviewed in the United States on September 2, 2025
D
Verified Purchase
Donna W
West Palm Beach, US
★★★★★ 5
Excellent heavy duty squeaker toy
Color: Green, Size: Large(50-90 lbs)
My German Shepherd LOVES this noisy toy. It is extremely well made, durable, LOUD, and heavy. I'm hoping this toy lasts much longer than the grunting pig that he absolutely loves, but tend to stop squeaking within a day or so. Definitely worth the money!
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Reviewed in the United States on April 15, 2026

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